What is MPV?
Monkeypox is a rare disease that is caused by infection with Monkeypox virus (MPV). Howard Brown Health provides vaccination, treatment, testing, and education for MPV. MPV can cause painful and potentially scarring blisters, rash, and swelling. Swelling from MPV in the mouth, throat, urethra, or anus can be extremely painful and possibly dangerous.
MPV usually begins with the below symptoms:
- Muscle aches
- Swollen lymph nodes
Within one to three days after the appearance of fever, a rash develops. It may begin anywhere such as the genitals, genital area, butt, back, chest, hands, or face. The rash may also appear where it is hard to see such in anus/rectum, mouth, throat, and/or urethra. Afterwards, sores can begin to develop over a period of 14-21 days. The severity of illness depends upon a person’s health, how they were exposed, and the strain of the virus. Typically, MPV symptoms last for 14-28 days. For examples of what MPV rash looks like, visit the CDC.gov.
MPV spreads from:
- Skin-to-skin contact, shared bedding, sexual contact, towels, and clothing.
- Prolonged exposure to droplets (from coughing or sneezing) of someone infected with MPV.
Due to a national shortage of MPV vaccines, it is important to take steps to prevent the spread of MPV.
- Your skin for bumps, blisters, or rash that may look like pimples.
- Genital areas, around the anus, trunk, face, hands and back.
- Yourself and your partners.
- Rash may be in the mouth, urethra, and/or rectum. Some or all symptoms may be present during MPV infection. Isolate if you experience fever, swollen lymph nodes, and/or rash, which may or may not be painful.
- Do not share bedding/towels and avoid skin-to-skin contact.
- Wear a mask around others.
- Whenever possible, limit the number of sex partners. A tight or closed network of partners may help reduce your risk of infection.
- Avoid sex with partners whose MPV status is unknown.
Vaccination for MPV
Howard Brown has received a limited supply of MPV vaccines to administer to qualifying patients.
The Chicago Department of Public Health (CDPH) recently updated guidelines regarding administering the Jynneos MPV vaccine (vaccine for smallpox and monkeypox). The current recommendation encourages healthcare providers to give a single dose of Jynneos to all who are eligible as soon as possible. Starting 7/18/2022, Howard Brown will administer one dose of Jynneos to eligible people as indicated by CDPH. We will offer subsequent doses upon further guidance from CDPH.
CDPH has provided the below guidelines to help determine vaccine eligibility. First doses of the vaccine are currently being prioritized until more vaccine becomes available.
The MPV vaccine is available to people who:
- Have had close physical contact with someone or an intimate partner who was diagnosed with MPV
- Gay men, bisexual men, and trans women who have sex with men
AND also one of the following:
- Have had or anticipate having sexual contact with gay or bisexual men at social venues
- Have had or anticipate having sexual contact for work or income
- Have had or anticipate having intimate or sexual contact with multiple or anonymous partners
Howard Brown Health now offers self-scheduling for vaccinations against monkeypox virus (MPV) at select clinic locations. If you fit the above criteria, click below to self-schedule your MPV vaccine appointment.
Please note that the number of available appointments is currently limited due to vaccine supply. Additional appointment slots will be opened as more supply becomes available. If you have any questions or concerns, call us at 872.269.3600 for more information.
Testing for MPV
CDPH recommends MPV screening for patients who meet the following criteria:
- People experiencing MPV symptoms, such as bumps, rash, or lesions that can be swabbed for testing.
There is no other MPV test available. If you meet the above criteria, call us at 773.388.1600 to schedule an MPV screening appointment. MPV screening appointments last about 20 minutes.
Treatment for MPV
Tecovirimat (TPOXX) is an available treatment for qualifying people with severe MPV. Because TPOXX is available through the CDC’s Expanded Access Investigational New Drug (EA-IND) protocol, we are required to obtain written informed consent prior to starting the medication. Only a small percentage of people with MPV will be eligible for treatment with TPOXX.
Eligibility for TPOXX includes:
- Experiencing severe disease such as hemorrhagic disease, lesions that are extensive, sepsis, encephalitis, or other conditions requiring hospitalization.
- Being at high risk of severe disease including people with immunocompromising conditions, such as recent organ transplant or on cancer-suppressing drugs; people who are pregnant or breastfeeding; people with gastroenteritis with severe nausea/vomiting, diarrhea, or dehydration; and people with infections involving accidental implantation in eyes, mouth, or other anatomic areas where MPV virus infection might constitute a special hazard (e.g., the genitals or anus).
Talk to your healthcare provider to determine if you are eligible for MPV treatment with TPOXX.
Tips for Recovery
If you have screened positive for MPV or are experiencing MPV symptoms, it is important to do what you can to minimize the chance of exposure to others.
- Self-isolate as much as possible until you are no longer experiencing symptoms.
- If you have lesions or a rash, cover them with clothing or a soft cloth when interacting with others or leaving your home.
- Do not share your bedding, towels, clothes, or other fabrics with others. Wash and dry your used bedding, towels, and clothing after use.
- Avoid skin-to-skin contact with others and use a face mask around others to minimize their risk of infection from large droplets from coughing or sneezing.
- Supportive care for any rash or lesions includes drinking plenty of fluids, pain management, and prevention or treatment of bacterial infections.
Proctitis is painful inflammation of the rectum lining and has been seen in cases of MPV.
Supportive care for anal/rectal inflammation includes drinking plenty of fluids, pain management, and prevention or treatment of bacterial infections. With early precautions and care, proctitis can be manageable at home.
For painful anal/rectal lesions, a warm sitz bath (soaking the butt in a tub of warm water) lasting at least 10 minutes several times per day can help. Topical benzocaine/lidocaine gels or creams may also provide temporary relief. If going to the bathroom is painful, stool softeners may also help. Pain from MPV proctitis may require prescription medications, in which case stool softeners may also be helpful to counteract constipation.
Proctitis can occur with internal lesions or bleeding. It is often manageable with appropriate supportive care, but it can become severe. If you have rectal bleeding with MPV or difficulty managing your pain, talk to your healthcare provider to work on a care plan that works for you. If you are experiencing severe bleeding, please call 911.
MPV Informational Resources
- Howard Brown Health MPV Fact Sheet (English PDF)
- Howard Brown Health MPV Fact Sheet (Spanish PDF)
- CDPH – Get the Facts: Monkeypox (chicago.gov)
- Infectious Disease Society of America MPV Fact sheet (English PDF)
- Infectious Disease Society of America MPV Fact sheet (Spanish PDF)
- CDC Infosheet – “Monkeypox and Safer Sex” (English PDF)