What is MPV?

Monkeypox is a rare disease that is caused by infection with Monkeypox virus (MPV). Howard Brown Health provides vaccination, treatment, testing, and education for MPV. MPV can cause painful and potentially scarring blisters, rash, and swelling. Swelling from MPV in the mouth, throat, urethra, or anus can be extremely painful and possibly dangerous.  

MPV usually begins with the below symptoms: 

Within one to three days after the appearance of fever, a rash develops. It may begin anywhere such as the genitals, genital area, butt, back, chest, hands, or face. The rash may also appear where it is hard to see such in anus/rectum, mouth, throat, and/or urethra. Afterwards, sores can begin to develop over a period of 14-21 days. The severity of illness depends upon a person’s health, how they were exposed, and the strain of the virus. Typically, MPV symptoms last for 14-28 days. For examples of what MPV rash looks like, visit the CDC.gov. 

MPV spreads from: 

MPV Prevention 

Due to a national shortage of MPV vaccines, it is important to take steps to prevent the spread of MPV. 

Vaccination for MPV

Howard Brown has received a limited supply of MPV vaccines to administer to qualifying patients.

The Chicago Department of Public Health (CDPH) recently updated guidelines regarding administering the Jynneos MPV vaccine (vaccine for smallpox and monkeypox). The current recommendation encourages healthcare providers to give a single dose of Jynneos to all who are eligible as soon as possible. Starting 7/18/2022, Howard Brown will administer one dose of Jynneos to eligible people as indicated by CDPH. We will offer subsequent doses upon further guidance from CDPH. 

You can find the official update from CDPH here.

CDPH has provided the below guidelines to help determine vaccine eligibility. First doses of the vaccine are currently being prioritized until more vaccine becomes available. 

The MPV vaccine is available to people who: 


AND also one of the following:

Howard Brown Health now offers self-scheduling for vaccinations against monkeypox virus (MPV) at select clinic locations. If you fit the above criteria, click below to self-schedule your MPV vaccine appointment.

Please note that the number of available appointments is currently limited due to vaccine supply. Additional appointment slots will be opened as more supply becomes available. If you have any questions or concerns, call us at 872.269.3600 for more information. 

Testing for MPV

CDPH recommends MPV screening for patients who meet the following criteria: 

There is no other MPV test available. If you meet the above criteria, call us at 773.388.1600 to schedule an MPV screening appointment. MPV screening appointments last about 20 minutes. 

Treatment for MPV 

Tecovirimat (TPOXX) is an available treatment for qualifying people with severe MPV. Because TPOXX is available through the CDC’s Expanded Access Investigational New Drug (EA-IND) protocol, we are required to obtain written informed consent prior to starting the medication. Only a small percentage of people with MPV will be eligible for treatment with TPOXX.  

Eligibility for TPOXX includes: 

Talk to your healthcare provider to determine if you are eligible for MPV treatment with TPOXX. 

Tips for Recovery

If you have screened positive for MPV or are experiencing MPV symptoms, it is important to do what you can to minimize the chance of exposure to others.  


Proctitis is painful inflammation of the rectum lining and has been seen in cases of MPV. 

Supportive care for anal/rectal inflammation includes drinking plenty of fluids, pain management, and prevention or treatment of bacterial infections. With early precautions and care, proctitis can be manageable at home. 

For painful anal/rectal lesions, a warm sitz bath (soaking the butt in a tub of warm water) lasting at least 10 minutes several times per day can help. Topical benzocaine/lidocaine gels or creams may also provide temporary relief. If going to the bathroom is painful, stool softeners may also help. Pain from MPV proctitis may require prescription medications, in which case stool softeners may also be helpful to counteract constipation.  

Proctitis can occur with internal lesions or bleeding. It is often manageable with appropriate supportive care, but it can become severe. If you have rectal bleeding with MPV or difficulty managing your pain, talk to your healthcare provider to work on a care plan that works for you. If you are experiencing severe bleeding, please call 911. 

MPV Informational Resources



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