DoxyPEP for STI prevention: morning-after pills that can help prevent syphilis, chlamydia, and gonorrhea

What is DoxyPEP?

DoxyPEP is a post-exposure preventative treatment for syphilis, chlamydia, and gonorrhea. Think of it as a morning-after pill but for bacterial STIs instead of pregnancy: take one dose after a condomless sexual encounter to greatly reduce your risk of contracting bacterial STIs.

DoxyPEP does NOT help prevent:

Who should consider DoxyPEP?

You should consider DoxyPEP if you were assigned male at birth, are at least 12 years old, and:

Although current research has shown that DoxyPEP is only effective for people meeting these criteria, we know that people who haven’t had a recent STI or were assigned female at birth may still be interested in adding DoxyPEP to their STI prevention toolkit. We encourage anyone who believes they may benefit from DoxyPEP to discuss the risks and benefits with their Howard Brown provider to see if it may be an option for them.

How can I get DoxyPEP?

  1. Make sure you’re eligible to take DoxyPEP (see “Who should consider DoxyPEP?” above)
  2. Schedule a routine primary care visit at a Howard Brown Health location
  3. Tell your scheduler or indicate in your online submission that you’re interested in starting DoxyPEP
  4. Attend your appointment: the provider will do STI testing and basic bloodwork to confirm your eligibility
  5. Once your test results come back and your eligibility is confirmed, we will provide you with a doxycycline prescription
  6. Pick up your prescription at a Howard Brown pharmacy (or your local pharmacy)
  7. Keep the bottle in your medicine cabinet or on your nightstand until you need it!

How do I take DoxyPEP?

Just remember that it’s 3, 2, 1!

Within three days, take two tabs, just one time

In other words:

When taking DoxyPEP, you should also keep in mind that:

What else should I know before starting DoxyPEP?

What should I know for after I start DoxyPEP?


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