In the summer of 2019, Four Corners conducted eight focus groups, two in each city of participating sites, in order to explore health and research priorities, participants’ prior experiences with research, and preferences for research dissemination. Focus groups were facilitated by two TNB project staff and included 65 participants, all of whom were at least eighteen years of age and self-identified as transgender, nonbinary, or gender nonconforming. Participants were recruited via flyers posted at the four FQHCs and social media advertisements. Focus groups were audio recorded and transcribed.